Multifunctional nano-bio INterfaces wIth deep braiN reGions
MINING - PROJECT GOALS
The main objectives of MINING are:
Devise a novel generation of neural endoscopes based on nanophotonics, enabling simultaneous (i) high-resolution functional imaging of neural signals, (ii) label-free optical monitoring of chemical compounds from both wide and localized brain volumes and (iii) optogenetic and thermoplasmonic modulation of neural functions with cellular resolution;
Integration of organic electrochemical transistors on the devised endoscopes, generating a novel optoelectrical neural interface with cellular resolution based on active electronics;
Development of methods for spatial-resolved multifunctional studies, to demonstrate the power of MINING endoscopes to reveal so far hidden patterns of electrochemical functional dynamics in the living mouse brain.